MIT senior Katie Spivakovsky has been selected as a 2026-27 Churchill Scholar and will undertake an MPhil in biological sciences at the Wellcome Sanger Institute at Cambridge University in the U.K. this fall. Spivakovsky, who is double-majoring in biological engineering and artificial intelligence, with minors in mathematics and biology, aims to integrate computation and bioengineering […]
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The way the brain develops can shape us throughout our lives, so neuroscientists are intensely curious about how it happens. A new study by researchers in The Picower Institute for Learning and Memory at MIT that focused on visual cortex development in mice reveals that an important class of neurons follows a set of rules […]
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Researchers in Class of 1942 Professor of Chemistry Matthew D. Shoulders’ lab have uncovered a sinister hidden mechanism that can allow cancer cells to survive (and, in some cases, thrive) even when hit with powerful drugs. The secret lies in a cellular “safety net” that gives cancer the freedom to develop aggressive mutations. This fascinating intersection between […]
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MIT Professor Emeritus Richard O. Hynes PhD ’71, a cancer biologist whose discoveries reshaped modern understandings of how cells interact with each other and their environment, passed away on Jan. 6. He was 81. Hynes is best known for his discovery of integrins, a family of cell-surface receptors essential to cell–cell and cell–matrix adhesion. He […]
Read MoreAt MIT, a strong spirit of mentorship shapes how students learn, collaborate, and imagine the future. In a time of accelerating change — from breakthroughs in artificial intelligence to the evolving realities of global research and work — guidance for technical challenges and personal growth is more important than ever. The Committed to Caring (C2C) […]
Read MoreFor decades, scientists with big questions about biology have found answers in a tiny worm. That worm — a millimeter-long creature called Caenorhabditis elegans — has helped researchers uncover fundamental features of how cells and organisms work. The impact of that work is enormous: Discoveries made using C. elegans have been recognized with four Nobel […]
Read MoreOne of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous. The researchers found that in response to a high-fat diet, mature hepatocytes in the liver revert to an immature, stem-cell-like […]
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Today, out of an estimated 1 trillion species on Earth, 99.999 percent are considered microbial — bacteria, archaea, viruses, and single-celled eukaryotes. For much of our planet’s history, microbes ruled the Earth, able to live and thrive in the most extreme of environments. Researchers have only just begun in the last few decades to contend […]
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All starting from the same DNA, neurons ultimately take on individual characteristics in the brain and body. Differences in which genes they transcribe into RNA help determine which type of neuron they become, and from there, a new MIT study shows, individual cells edit a selection of sites in those RNA transcripts, each at their […]
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During early development, tissues and organs begin to bloom through the shifting, splitting, and growing of many thousands of cells. A team of MIT engineers has now developed a way to predict, minute by minute, how individual cells will fold, divide, and rearrange during a fruit fly’s earliest stage of growth. The new method may […]
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In February, President Sally Kornbluth announced the appointment of Professor Angela Koehler as faculty director of the MIT Health and Life Sciences Collaborative (MIT HEALS), with professors Iain Cheeseman and Katharina Ribbeck as associate directors. Since then, the leadership team has moved quickly to shape HEALS into an ambitious, community-wide platform for catalyzing research, translation, […]
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The School of Science welcomed 11 new faculty members in 2024. Shaoyun Bai researches symplectic topology, the study of even-dimensional spaces whose properties are reflected by two-dimensional surfaces inside them. He is interested in this area’s interaction with other fields, including algebraic geometry, algebraic topology, geometric topology, and dynamics. He has been developing new tool […]
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Around 25 million Americans have rare genetic diseases, and many of them struggle with not only a lack of effective treatments, but also a lack of good information about their disease. Clinicians may not know what causes a patient’s symptoms, know how their disease will progress, or even have a clear diagnosis. Researchers have looked […]
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Our muscles are nature’s actuators. The sinewy tissue is what generates the forces that make our bodies move. In recent years, engineers have used real muscle tissue to actuate “biohybrid robots” made from both living tissue and synthetic parts. By pairing lab-grown muscles with synthetic skeletons, researchers are engineering a menagerie of muscle-powered crawlers, walkers, […]
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Taking an audience of hundreds on a tour around the body, seven speakers at The Picower Institute for Learning and Memory’s symposium “Circuits of Survival and Homeostasis” Oct. 21 shared their advanced and novel research about some of the nervous system’s most evolutionarily ancient functions. Introducing the symposium that she arranged with a picture of […]
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Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they’re able to fill such disparate niches because molecular machinery can cut out and stitch together different segments of those instructions to create endlessly unique combinations. The ingenuity of using the same genes in different ways is made possible […]
Read More Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they’re able to fill such disparate niches because molecular machinery can cut out and stitch together different segments of those instructions to create endlessly unique combinations. The ingenuity of using the same genes in different ways is made possible […]
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For almost 30 years, Mary Gallagher has supported award-winning faculty members and their labs in the same way she tends the soil beneath her garden. In both, she pairs diligence and experience with a delight in the way that interconnected ecosystems contribute to the growth of a plant, or an idea, seeded in the right […]
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On Oct. 20 during its annual meeting, the National Academy of Medicine announced the election of 100 new members, including MIT faculty members Dina Katabi and Facundo Batista, along with three additional MIT alumni. Election to the National Academy of Medicine (NAM) is considered one of the highest honors in the fields of health and […]
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Nervous system functions, from motion to perception to cognition, depend on the active zones of neural circuit connections, or “synapses,” sending out the right amount of their chemical signals at the right times. By tracking how synaptic active zones form and mature in fruit flies, researchers at The Picower Institute for Learning and Memory at […]
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The MIT Schwarzman College of Computing welcomes 11 new faculty members in core computing and shared positions to the MIT community. They bring varied backgrounds and expertise spanning sustainable design, satellite remote sensing, decision theory, and the development of new algorithms for declarative artificial intelligence programming, among others. “I warmly welcome this talented group of […]
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Associate Professor Gene-Wei Li has accepted the position of associate head of the MIT Department of Biology, starting in the 2025-26 academic year. Li, who has been a member of the department since 2015, brings a history of departmental leadership, service, and research and teaching excellence to his new role. He has received many awards, […]
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Understanding how interactions between the central nervous system and the immune system contribute to problems of aging, including Alzheimer’s disease, Parkinson’s disease, arthritis, and more, can generate new leads for therapeutic development, speakers said at MIT’s symposium “The Neuro-Immune Axis and the Aging Brain” on Sept 18. “The past decade has brought rapid progress in […]
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One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells. MIT and Harvard Medical School researchers have now come up with a new way to engineer CAR-NK cells […]
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A diet rich in the amino acid cysteine may have rejuvenating effects in the small intestine, according to a new study from MIT. This amino acid, the researchers discovered, can turn on an immune signaling pathway that helps stem cells to regrow new intestinal tissue. This enhanced regeneration may help to heal injuries from radiation, […]
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A team of MIT geochemists has unearthed new evidence in very old rocks suggesting that some of the first animals on Earth were likely ancestors of the modern sea sponge. In a study appearing today in the Proceedings of the National Academy of Sciences, the researchers report that they have identified “chemical fossils” that may […]
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Gleevec, a cancer drug first approved for sale in 2001, has dramatically changed the lives of people with chronic myeloid leukemia. This form of cancer was once regarded as very difficult to combat, but survival rates of patients who respond to Gleevec now resemble that of the population at large. Gleevec is also a medicine […]
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Cancer cells have one relentless goal: to grow and divide. While most stick together within the original tumor, some rogue cells break away to traverse to distant organs. There, they can lie dormant — undetectable and not dividing — for years, like landmines waiting to go off. This migration of cancer cells, called metastasis, is […]
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A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones. However, the process carries a small chance of inserting errors that could be harmful. MIT researchers have now found a way to dramatically lower the error rate of prime editing, using modified versions of the […]
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When cells are healthy, we don’t expect them to suddenly change cell types. A skin cell on your hand won’t naturally morph into a brain cell, and vice versa. That’s thanks to epigenetic memory, which enables the expression of various genes to “lock in” throughout a cell’s lifetime. Failure of this memory can lead to […]
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The Whitehead Institute for Biomedical Research fondly remembers its founding director, David Baltimore, a former MIT Institute Professor and Nobel laureate who died Sept. 6 at age 87. With discovery after discovery, Baltimore brought to light key features of biology with direct implications for human health. His work at MIT earned him a share of […]
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