Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds. In a new study, MIT chemical engineers have harnessed artificial intelligence to optimize the development of new protein manufacturing processes, which could reduce the overall costs of developing and manufacturing these drugs. Using a large language model (LLM), […]
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The Abdul Latif Jameel Poverty Action Lab (J-PAL) at MIT has awarded funding to eight new research studies to understand how artificial intelligence innovations can be used in the fight against poverty through its new Project AI Evidence. The age of AI has brought wide-ranging optimism and skepticism about its effects on society. To realize […]
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For more than a decade, MIT Associate Professor Rafael Gómez-Bombarelli has used artificial intelligence to create new materials. As the technology has expanded, so have his ambitions. Now, the newly tenured professor in materials science and engineering believes AI is poised to transform science in ways never before possible. His work at MIT and beyond […]
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James J. Collins, the Termeer Professor of Medical Engineering and Science at MIT and faculty co-lead of the Abdul Latif Jameel Clinic for Machine Learning in Health, is embarking on a multidisciplinary research project that applies synthetic biology and generative artificial intelligence to the growing global threat of antimicrobial resistance (AMR). The research project is […]
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The signals that drive many of the brain and body’s most essential functions — consciousness, sleep, breathing, heart rate, and motion — course through bundles of “white matter” fibers in the brainstem, but imaging systems so far have been unable to finely resolve these crucial neural cables. That has left researchers and doctors with little […]
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3D bioprinting, in which living tissues are printed with cells mixed into soft hydrogels, or “bio-inks,” is widely used in the field of bioengineering for modeling or replacing the tissues in our bodies. The print quality and reproducibility of tissues, however, can face challenges. One of the most significant challenges is created simply by gravity […]
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Olympic figure skating looks effortless. Athletes sail across the ice, then soar into the air, spinning like a top, before landing on a single blade just 4-5 millimeters wide. To help figure skaters land quadruple axels, Salchows, Lutzes, and maybe even the elusive quintuple without looking the least bit stressed, Jerry Lu MFin ’24 developed […]
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Most materials have an inherent capacity to handle heat. Plastic, for instance, is typically a poor thermal conductor, whereas materials like marble move heat more efficiently. If you were to place one hand on a marble countertop and the other on a plastic cutting board, the marble would conduct more heat away from your hand, […]
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A firm that wants to use a large language model (LLM) to summarize sales reports or triage customer inquiries can choose between hundreds of unique LLMs with dozens of model variations, each with slightly different performance. To narrow down the choice, companies often rely on LLM ranking platforms, which gather user feedback on model interactions […]
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Scientists on the Thwaites Glacier attempted to install equipment beneath the ice to better understand how it is melting. Our climate reporter Raymond Zhong walks us through their landmark experiment and the bittersweet outcome. By Raymond Zhong, Chang W. Lee, Christina Thornell, Jon Miller, Stephanie Swart and Shafik Quoraishee February 6, 2026
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“So let’s stop the games,” she continued. “If you want this fight, [Representative James Comer], let’s have it—in public. You love to talk about transparency. There’s nothing more transparent than a public hearing, cameras on. We will be there.” Responding to Clinton, Comer told Fox that the closed-door deposition had already been agreed to, and […]
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In a wide-ranging live conversation, MIT President Sally Kornbluth joined Jim Braude and Margery Eagan live in studio for GBH’s Boston Public Radio on Thursday, February 5. They talked about MIT, the pressures facing America’s research enterprise, the importance of science, that Congressional hearing on antisemitism in 2023, and more – including Sally’s experience as a […]
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Early in the 1969 film “Midnight Cowboy,” Dustin Hoffman, playing the character of Ratso Rizzo, crosses a Manhattan street and angrily bangs on the hood of an encroaching taxi. Hoffman’s line — “I’m walking here!” — has since been repeated by thousands of New Yorkers. Where cars and people mix, tensions rise. And yet, governments […]
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Oxygen is a vital and constant presence on Earth today. But that hasn’t always been the case. It wasn’t until around 2.3 billion years ago that oxygen became a permanent fixture in the atmosphere, during a pivotal period known as the Great Oxidation Event (GOE), which set the evolutionary course for oxygen-breathing life as we […]
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The ability to use language to communicate is one of things that makes us human. At MIT’s McGovern Institute for Brain Research, scientists led by Evelina Fedorenko have defined an entire network of areas within the brain dedicated to this ability, which work together when we speak, listen, read, write, or sign. Much of the […]
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Whether you’re a scientist brainstorming research ideas or a CEO hoping to automate a task in human resources or finance, you’ll find that artificial intelligence tools are becoming the assistants you didn’t know you needed. In particular, many professionals are tapping into the talents of semi-autonomous software systems called AI agents, which can call on AI […]
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A longstanding goal of immunotherapies and vaccine research is to induce antibodies in humans that neutralize deadly viruses such as HIV and influenza. Of particular interest are antibodies that are “broadly neutralizing,” meaning they can in principle eliminate multiple strains of a virus such as HIV, which mutates rapidly to evade the human immune system. […]
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Metamaterials — materials whose properties are primarily dictated by their internal microstructure, and not their chemical makeup — have been redefining the engineering materials space for the last decade. To date, however, most metamaterials have been lightweight options designed for stiffness and strength. New research from the MIT Department of Mechanical Engineering introduces a computational design framework to […]
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You can tell a lot about a material based on the type of light you shine at it: Optical light illuminates a material’s surface, while X-rays reveal its internal structures and infrared captures a material’s radiating heat. Now, MIT physicists have used terahertz light to reveal inherent, quantum vibrations in a superconducting material, which have […]
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What if ultrasound imaging is no longer confined to hospitals? Patients with chronic conditions, such as hypertension and heart failure, could be monitored continuously in real-time at home or on the move, giving health care practitioners ongoing clinical insights instead of the occasional snapshots — a scan here and a check-up there. This shift from […]
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More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead to the development of more severe liver disease that causes inflammation and fibrosis. In hopes of discovering new treatments for these liver diseases, MIT engineers […]
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The plastic bottle you just tossed in the recycling bin could provide structural support for your future house. MIT engineers are using recycled plastic to 3D print construction-grade beams, trusses, and other structural elements that could one day offer lighter, modular, and more sustainable alternatives to traditional wood-based framing. In a paper published in the […]
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The way the brain develops can shape us throughout our lives, so neuroscientists are intensely curious about how it happens. A new study by researchers in The Picower Institute for Learning and Memory at MIT that focused on visual cortex development in mice reveals that an important class of neurons follows a set of rules […]
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Generative artificial intelligence models have been used to create enormous libraries of theoretical materials that could help solve all kinds of problems. Now, scientists just have to figure out how to make them. In many cases, materials synthesis is not as simple as following a recipe in the kitchen. Factors like the temperature and length […]
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For people who are at high risk of developing breast cancer, frequent screenings with ultrasound can help detect tumors early. MIT researchers have now developed a miniaturized ultrasound system that could make it easier for breast ultrasounds to be performed more often, either at home or at a doctor’s office. The new system consists of […]
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MIT researchers have designed silicon structures that can perform calculations in an electronic device using excess heat instead of electricity. These tiny structures could someday enable more energy-efficient computation. In this computing method, input data are encoded as a set of temperatures using the waste heat already present in a device. The flow and distribution […]
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In its first moments, the infant universe was a trillion-degree-hot soup of quarks and gluons. These elementary particles zinged around at light speed, creating a “quark-gluon plasma” that lasted for only a few millionths of a second. The primordial goo then quickly cooled, and its individual quarks and gluons fused to form the protons, neutrons, […]
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new video loaded: Setting Foot on the Melting Thwaites Glacier <img src="https://static01.nyt.com/images/2026/01/21/arts/ray-thwaites/ray-thwaites-jumbo.jpg?auto=webp&quality=75" data-testid="betamax-poster" sizes="(width Bad weather delayed expedition scientists’ efforts to set up camp on Thwaites Glacier in Antarctica and take measurements to determine how quickly it is melting. After the skies cleared, our journalists, Raymond Zhong and Chang W. Lee, took us along for […]
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Researchers in Class of 1942 Professor of Chemistry Matthew D. Shoulders’ lab have uncovered a sinister hidden mechanism that can allow cancer cells to survive (and, in some cases, thrive) even when hit with powerful drugs. The secret lies in a cellular “safety net” that gives cancer the freedom to develop aggressive mutations. This fascinating intersection between […]
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A new computational model of the brain based closely on its biology and physiology not only learned a simple visual category learning task exactly as well as lab animals, but even enabled the discovery of counterintuitive activity by a group of neurons that researchers working with animals to perform the same task had not noticed […]
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MIT researchers have identified significant examples of machine-learning model failure when those models are applied to data other than what they were trained on, raising questions about the need to test whenever a model is deployed in a new setting. “We demonstrate that even when you train models on large amounts of data, and choose […]
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