Recognizing his research advancing understanding of how the brain changes with experience by altering the strength of connections among neurons, a phenomenon called “synaptic plasticity,” the Society for Neuroscience (SfN) recently named Mark Bear, Picower Professor at MIT, a co-recipient of the 2023 Julius Axelrod Prize. The prize honors scientists with distinguished achievements in the broad field […]
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Spanning computer science, mechanical engineering, biological engineering, neuroscience, and other disciplines, presenters at MIT’s Aging Brain Initiative Symposium Oct. 23 delivered a rich and diverse sampling of the university’s research to address a major global problem: neurodegenerative diseases such as Alzheimer’s and amyotrophic lateral sclerosis (ALS). “We still don’t completely understand the mechanism underlying the […]
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If anesthesiologists had a rigorous means to manage dosing, they could deliver less medicine, maintaining exactly the right depth of unconsciousness while reducing postoperative cognitive side effects in vulnerable groups like the elderly. But with myriad responsibilities for keeping anesthetized patients alive and stable as well as maintaining their profoundly unconscious state, anesthesiologists don’t have […]
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Hundreds of millions of people worldwide suffer from a vision condition called amblyopia, or lazy eye, with imbalanced vision in their two eyes. Unless this disabling condition is caught and treated at a young age, it’s rare for children to regain full vision, because the brain learns to turn off the input from the “lazy” […]
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Because figuring out what is new and what is familiar in what we see is such a critically important ability for prioritizing our attention, neuroscientists have spent decades trying to figure out how our brains are typically so good at it. Along the way they’ve made key observations that seem outright contradictory, but a new […]
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The National Academy of Medicine announced the election of 100 new members to join their esteemed ranks in 2023, among them five MIT faculty members and seven additional affiliates. MIT professors Daniel Anderson, Regina Barzilay, Guoping Feng, Darrell Irvine, and Morgen Shen were among the new members. Justin Hanes PhD ’96, Said Ibrahim MBA ’16, […]
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A new MIT study that focuses on a single cell in one of nature’s simplest nervous systems provides an in-depth illustration of how individual neurons can use multiple means to drive complex behaviors. In the C. elegans worm, which only has 302 nerve cells, the neuron HSN releases several chemicals and makes multiple connections along its length […]
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Alzheimer’s disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease. In hopes of discovering new targets for potential Alzheimer’s treatments, MIT researchers have performed the broadest analysis yet of the genomic, epigenomic, and transcriptomic changes that occur in […]
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Neurons are talkers. They each communicate with fellow neurons, muscles, or other cells by releasing neurotransmitter chemicals at “synapse” junctions, ultimately producing functions ranging from emotions to motions. But even neurons of the exact same type can vary in their conversational style. A new open-access study in Cell Reports by neurobiologists at The Picower Institute for Learning […]
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Last spring, the School of Science welcomed seven new faculty members. Erin Chen PhD ’11 studies the communication between microbes that reside on the surface of the human body and the immune system. She focuses on the largest organ: the skin. Chen will dissect the molecular signals of diverse skin microbes and their effects on […]
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Neuroscience discoveries ranging from the nature of memory to treatments for disease have depended on reading the minds of mice, so researchers need to truly understand what the rodents’ behavior is telling them during experiments. In a new study that examines learning from reward, MIT researchers deciphered some initially mystifying mouse behavior, yielding new ideas […]
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Though drug developers have achieved some progress in treating Alzheimer’s disease with medicines that reduce amyloid-beta protein, other problems of the disease, including inflammation, continue unchecked. In a new study, scientists at The Picower Institute for Learning and Memory at MIT describe a candidate drug that in human cell cultures and Alzheimer’s mouse models reduced […]
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Figuring out how hundreds of different kinds of brain cells develop from their unique expression of thousands of genes promises to not only advance understanding of how the brain works in health, but also what goes wrong in disease. A new MIT study that precisely probes this “molecular logic” in two neuron types of the Drosophila fruit […]
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