Nearly 150 years ago, scientists began to imagine how information might flow through the brain based on the shapes of neurons they had seen under the microscopes of the time. With today’s imaging technologies, scientists can zoom in much further, seeing the tiny synapses through which neurons communicate with one another, and even the molecules […]
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We’re in a protein craze, and it’s hard to ignore. Walk into any grocery store and you’ll find rows of protein-fortified energy bars, breakfast cereals, baked goods, snacks, even sports drinks. And on social media, influencers — many with medical or scientific degrees in their bios — claim that most people are woefully deficient. “Ladies, […]
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For many people, aging feels like it happens in stops and starts. After a period of smooth sailing, one day, seemingly out of the blue, you have achy knees. “You wake up in the morning and you suddenly feel old,” said Dr. Steve Hoffmann, a computational biology professor at the Leibniz Institute on Aging in […]
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Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, the most common genetically-caused autism spectrum disorder. The team showed that augmenting a novel type of neurotransmitter signaling reduced hallmarks of […]
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In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden’s lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a pair of new methods, they are expanding the capabilities of expansion microscopy — a high-resolution imaging technique the group introduced in 2015 — so […]
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A vast search of natural diversity has led scientists at MIT’s McGovern Institute for Brain Research and the Broad Institute of MIT and Harvard to uncover ancient systems with potential to expand the genome editing toolbox. These systems, which the researchers call TIGR (Tandem Interspaced Guide RNA) systems, use RNA to guide them to specific […]
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All biological function is dependent on how different proteins interact with each other. Protein-protein interactions facilitate everything from transcribing DNA and controlling cell division to higher-level functions in complex organisms. Much remains unclear, however, about how these functions are orchestrated on the molecular level, and how proteins interact with each other — either with other […]
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The Covid-19 vaccines were powerfully protective, preventing millions of deaths. But in a small number of people, the shots may have led to a constellation of side effects that includes fatigue, exercise intolerance, brain fog, tinnitus and dizziness, together referred to as “post-vaccination syndrome,” according to a small new study. Some people with this syndrome […]
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You’ve probably heard these two bits of nutrition advice: Eat more plants, and cut back on ultraprocessed foods. So where does that leave fake-meat burgers, sausages, nuggets and other products sold by companies like Beyond Meat and Impossible Foods? They are made from plants like soybeans and peas, but they are also highly processed. If […]
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Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each performing a specialized function. Researchers have long known that the structure of a protein determines what it can do. More recently, researchers are coming to appreciate that a protein’s localization is also critical […]
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A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility. Using the technology, the team was able to richly label large tissue samples in a single day. In their new study in Nature Biotechnology, they also demonstrate that […]
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Our solar system contains planets, dwarf planets, asteroids and comets — but only one world is known to harbor life. Scientists have long debated whether Earth is truly unique. Perhaps our planet just happened to have the right combination of ingredients, conditions and timing to allow life to emerge. But a pinch of grit from […]
Read MoreChronic diseases like Type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing. Treating chronic disease has proven difficult because there is not one simple […]
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