Tag: National Institutes of Health (NIH)

An implantable device could enable injection-free control of diabetes

One promising approach to treating Type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections. However, one major obstacle to this approach is that once the cells are implanted, they eventually run out of oxygen and stop producing insulin. To overcome […]

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Study decodes surprising approach mice take in learning

Neuroscience discoveries ranging from the nature of memory to treatments for disease have depended on reading the minds of mice, so researchers need to truly understand what the rodents’ behavior is telling them during experiments. In a new study that examines learning from reward, MIT researchers deciphered some initially mystifying mouse behavior, yielding new ideas […]

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How an archeological approach can help leverage biased data in AI to improve medicine

The classic computer science adage “garbage in, garbage out” lacks nuance when it comes to understanding biased medical data, argue computer science and bioethics professors from MIT, Johns Hopkins University, and the Alan Turing Institute in a new opinion piece published in a recent edition of the New England Journal of Medicine (NEJM). The rising […]

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MIT engineers design more powerful RNA vaccines

RNA vaccines against Covid-19 have proven effective at reducing the severity of disease. However, a team of researchers at MIT is working on making them even better. By tweaking the design of the vaccines, the researchers showed that they could generate Covid-19 RNA vaccines that produce a stronger immune response, at a lower dose, in […]

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Molecule reduces inflammation in Alzheimer’s models

Though drug developers have achieved some progress in treating Alzheimer’s disease with medicines that reduce amyloid-beta protein, other problems of the disease, including inflammation, continue unchecked. In a new study, scientists at The Picower Institute for Learning and Memory at MIT describe a candidate drug that in human cell cultures and Alzheimer’s mouse models reduced […]

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Study connects neural gene expression differences to functional distinctions

Figuring out how hundreds of different kinds of brain cells develop from their unique expression of thousands of genes promises to not only advance understanding of how the brain works in health, but also what goes wrong in disease. A new MIT study that precisely probes this “molecular logic” in two neuron types of the Drosophila fruit […]

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AI models are powerful, but are they biologically plausible?

Artificial neural networks, ubiquitous machine-learning models that can be trained to complete many tasks, are so called because their architecture is inspired by the way biological neurons process information in the human brain. About six years ago, scientists discovered a new type of more powerful neural network model known as a transformer. These models can […]

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Study explains how part of the nucleolus evolved

Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come together to form these assemblies within cells. MIT biologists have now discovered that a single scaffolding protein is responsible for the formation of one of these condensates, which […]

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