Tag: Drugs (Pharmaceuticals)

Will We Be Hostages to Drug Makers’ Covid Vaccine Pricing?

Yes, of course, Americans’ health is priceless, and reining in a deadly virus that has trashed the economy would be invaluable. But a Covid-19 vaccine will have an actual price tag. And given the prevailing business-centric model of American drug pricing, it could well be budget breaking, perhaps making it unavailable to many. The last […]

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It Paid Doctors Kickbacks. Now, Novartis Will Pay a $678 Million Settlement.

It picked up the tab at Daniel and Peter Luger, but the inducements for doctors didn’t end with those New York restaurants. There were fishing junkets, golf outings and round-table events at Hooters. And then there were the six-figure honorariums that the Novartis Pharmaceutical Corp. paid to several doctors who wrote thousands of prescriptions for […]

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House Votes to Limit Health Costs as Drug Maker Adds Price Tag to Virus Treatment

WASHINGTON — House Democrats, moving to sharpen the distinction between themselves and Republicans as the coronavirus pandemic rages, passed legislation on Monday that would ensure that Americans paid no more than 8.5 percent of their income for health insurance and would allow the government to negotiate prices with drug makers. The House passed the bill, […]

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Lotus Flower Plague-Repellent Pills and Other Gifts From China

CHICAGO — “The motherland is by your side” read the message printed on the plastic envelope. The characters were set in bright yellow against a crimson background, the same colors as on China’s national flag. “Genuine affection from 10,000 miles away.” This spring, as the novel coronavirus became a global pandemic, the Chinese government started […]

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Breakthrough Drug for Covid-19 May Be Risky for Mild Cases

Scientists in Britain announced a major breakthrough in the battle against the coronavirus last week, reporting they had found the first drug to reduce deaths among critically ill Covid-19 patients. The results were first made public in a sparsely detailed news release. Now the full study, neither peer reviewed nor published yet, has been posted […]

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Gilead to Test a Version of Remdesivir That Can Be Inhaled

The American biopharmaceutical company Gilead Sciences will soon start trials of an inhalable version of remdesivir, an antiviral drug that has shown promise as a therapeutic against the coronavirus in early trials, according to a statement released Monday. Remdesivir is currently given intravenously, which restricts its use to hospital settings. “That’s been the limitation” with […]

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Tsunami or Ripple? The Pandemic’s Mental Toll Is an Open Question

The psychological fallout from the coronavirus pandemic has yet to fully show itself, but some experts have forecast a tsunami of new disorders, and news accounts have amplified that message. The World Health Organization warned in May of “a massive increase in mental health conditions in the coming months,” wrought by anxiety and isolation. Digital […]

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Older Adults May Be Left Out of Some Covid-19 Trials

Picture the day — in six months, a year and a half or in 2023 — when university researchers or a pharmaceutical company announces a breakthrough against the virus that causes Covid-19. Maybe it’s a successful vaccine or an effective treatment, a discovery that brings hope and relief — especially to the older adults most […]

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Coronavirus Attacks the Lungs. A Federal Agency Just Halted Funding for New Lung Treatments.

When the coronavirus kills, it attacks the lungs, filling them with fluid and robbing the body of oxygen. In chest X-rays, clear lungs turn white, a sign of how dangerously sick patients are. But earlier this month, the Biomedical Advanced Research and Development Authority, or BARDA, a federal health agency, abruptly notified companies and researchers […]

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Trump Hydroxychloroquine Push Secured Millions of Likely Useless Coronavirus Pills

WASHINGTON — The Food and Drug Administration’s abrupt decision this week to revoke an emergency waiver for two malaria drugs promoted by President Trump as potential “game changers” against the coronavirus has left 66 million doses stranded in the federal stockpile — and officials do not yet know what they will do with them. The […]

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Dexamethasone Reduces Coronavirus Deaths, Scientists Say

LONDON — In an unexpected glimmer of hope amid an expanding pandemic, scientists at the University of Oxford said on Tuesday that an inexpensive and commonly available drug reduced deaths in patients with severe Covid-19, the illness caused by the coronavirus. If the finding is borne out, the drug, a steroid called dexamethasone, would be […]

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The Pandemic Claims New Victims: Prestigious Medical Journals

One study promised that popular blood-pressure drugs were safe for people infected with the coronavirus. Another paper warned that anti-malaria drugs endorsed by President Trump actually were dangerous to these patients. The studies, published in the New England Journal of Medicine and The Lancet, were retracted shortly after publication, following an outcry from researchers who […]

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Guaranteed Ingredient in Any Coronavirus Vaccine? Thousands of Volunteers

Not long after researchers completed their work with mice, guinea pigs, ferrets and monkeys, Human Subject 8, an art director for a software company in Missouri, received an injection. Four days later, her sister, a schoolteacher, became Subject 14. Together, the sisters make up about 5 percent of the first ever clinical trial of a […]

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Coronavirus Can Set Off a ‘Cytokine Storm.’ These Drugs May Calm It.

Many coronavirus patients seem to get better at first, then rapidly decline and are overtaken by an overwhelming immune response that causes the body to turn on itself. This “cytokine storm” was once an arcane phenomenon familiar mainly to rheumatologists who study when and how the immune system’s safeguards fail. But it has become increasingly […]

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Doctors Heavily Overprescribed Antibiotics Early in the Pandemic

The desperately ill patients who deluged the emergency room at Detroit Medical Center in March and April exhibited the telltale symptoms of the coronavirus: high fevers and infection-riddled lungs that left them gasping for air. With few treatment options, doctors turned to a familiar intervention: broad-spectrum antibiotics, the shot-in-the-dark medications often used against bacterial infections […]

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Two Huge Covid-19 Studies Are Retracted After Scientists Sound Alarms

The studies, published in renowned scientific journals, produced astounding results and altered the course of research into the coronavirus pandemic. One undercut President Trump’s claim that certain antimalarial drugs cure Covid-19, the illness caused by the virus, concluding that the medications in fact were dangerous to patients. The other found that some blood pressure drugs […]

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Trump ‘Remains Healthy’ After Taking Hydroxychloroquine, His Doctor Says

WASHINGTON — President Trump’s cardiac health was closely monitored while he took a two-week course of hydroxychloroquine to prevent contracting Covid-19, his physician said on Wednesday, and the president completed the treatment “safely and without side effects.” That assessment was contained in a summary of Mr. Trump’s health compiled by Dr. Sean Conley, the White […]

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Trump Narrows Search for Coronavirus Vaccine to Five Firms

WASHINGTON — The Trump administration has selected five companies as the most likely candidates to produce a vaccine for the coronavirus, senior officials said, a critical step in the White House’s effort to deliver on its promise of being able to start widespread inoculation of Americans by the end of the year. By winnowing the […]

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Tests for Coronavirus Vaccine Need This Ingredient: Horseshoe Crabs

For decades, drug companies have depended on a component in the blood of the horseshoe crab to test injectable medicines, including vaccines, for dangerous bacterial contaminants called endotoxins. Conservationists and some businesses have pushed for wide acceptance of an alternative test, to protect the horseshoe crabs and birds that feed on their eggs. Earlier this […]

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Big Pharmacy Chains Also Fed the Opioid Epidemic, Court Filing Says

Through years of lawsuits and rising public anger over the opioid epidemic, the big American pharmacy retailers have largely eluded scrutiny. But a new court filing Wednesday morning asserts that pharmacies including CVS, Rite Aid, Walgreens and Giant Eagle as well as those operated by Walmart were as complicit in perpetuating the crisis as the […]

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Remdesivir Coronavirus Trial: Federal Scientists Finally Publish Data

Nearly a month after federal scientists claimed that an experimental drug had helped patients severely ill with the coronavirus, the research has been published. The drug, remdesivir, was quickly authorized by the Food and Drug Administration for treatment of coronavirus patients, and hospitals rushed to obtain supplies. But until now, researchers and physicians had not […]

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Treating Mild Coronavirus Cases Could Help Save Everyone

The president’s decision is puzzling. And yet it does highlight the urgent need to devote more attention and resources to drugs that can prevent Covid-19 or stop mild cases from getting worse. To date, about a dozen studies on therapies for Covid-19 have been published; all were conducted on hospitalized patients, typically with severe symptoms. […]

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$1.2 Billion From U.S. to Drugmaker to Pursue Coronavirus Vaccine

The deal with AstraZeneca is the fourth and by far the largest vaccine research agreement that the department has disclosed. The money will pay for a Phase 3 clinical trial of a potential vaccine in the United States this summer with about 30,000 volunteers. The H.H.S. statement said the agency and AstraZeneca “are collaborating to […]

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Trump’s Inaccurate Claims on Hydroxychloroquine

“Hydroxychloroquine is used by thousands and thousands of front-line workers, so that hopefully they don’t catch this horrible disease or whatever you want to call it.”— in a cabinet meeting on Tuesday This lacks evidence. It is certainly possible that some doctors and health care workers are still taking hydroxychloroquine as a preventive treatment, but […]

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Trump’s Vaccine Chief Has Vast Ties to Drug Industry, Posing Possible Conflicts

The chief scientist brought on to lead the Trump administration’s vaccine efforts has spent the last several days trying to disentangle pieces of his stock portfolio and his intricate ties to big pharmaceutical interests, as critics point to the potential for significant conflicts of interest. The scientist, Moncef Slaoui, is a venture capitalist and a […]

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What to Expect When a Coronavirus Vaccine Finally Arrives

On a spring morning in 1955, a pair of press officers greeted a mob of reporters in a stately hall on the University of Michigan campus. The officers had hot news: A clinical trial of the long-awaited polio vaccine had proved it to be safe and effective. The reporters nearly rioted in their scramble to […]

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What to Expect When a Coronavirus Vaccine Finally Arrives

On a spring morning in 1955, a pair of press officers greeted a mob of reporters in a stately hall on the University of Michigan campus. The officers had hot news: A clinical trial of the long-awaited polio vaccine had proved it to be safe and effective. The reporters nearly rioted in their scramble to […]

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The Risks of Trump’s Hydroxychloroquine Hype

President Trump revealed on Monday that despite warnings from the Food and Drug Administration, he said he has been taking hydroxychloroquine for about a week and a half as a preventive measure. The F.D.A. warnings about hydroxychloroquine (and the related drug chloroquine) follow studies of the drug that have so far largely proved disappointing. While […]

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Trump to Tap New Company to Make Covid-19 Drugs in the U.S.

WASHINGTON — The Trump administration will announce on Tuesday that it has signed a $354 million four-year contract with a new company in Richmond, Va., to manufacture generic medicines and pharmaceutical ingredients that are needed to treat Covid-19 but are now made overseas, mostly in India and China. The contract, awarded to Phlow Corp. by […]

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Trump Says He’s Taking Hydroxychloroquine, Prompting Warning From Health Experts

WASHINGTON — President Trump said on Monday that he had been taking hydroxychloroquine, an antimalarial drug the Food and Drug Administration warned could cause serious heart problems for coronavirus patients. He said he was taking the drug as a preventive measure and continued to test negative for the coronavirus. “All I can tell you is […]

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